Before writing, click the or "Fix CheckSum" button. DMIEdit 5.20 automatically recalculates the DMI table header checksum. If you skip this, the BIOS will reject the change or crash.
How to Edit DMI information in the BIOS? - MSI Global English Forum dmiedit 5.20
Version 5.20 includes more verbose error handling. Here are frequent issues and solutions: Unlocking the BIOS: Why DMIEDIT 5
The tool will fail if not run with elevated privileges. dmiedit 5.20
are you trying to edit (Serial Number, UUID, Product Name)? Are you doing this in Windows or via a bootable USB ?