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DAVID (Database for Annotation, Visualization and Integrated Discovery) — Overview & resources
Developed by the Laboratory of Human Retrovirology and Immunoinformatics (LHRI) at the NIH, DAVID was created to bridge the gap between large-scale data acquisition and biological meaning. The tool was designed to systematically extract biological themes from lists of genes or proteins.
functional annotation and enrichment analysis
The platform is primarily used for , helping researchers understand the "biological themes" behind high-throughput genomic data. david bioinformatics resources
For the wet-lab biologist holding a printout of differentially expressed genes, DAVID is the fastest way to turn that list into a plausible biological story. For the bioinformatician, DAVID serves as a reliable validation tool to cross-check pipeline outputs. Gene Ontology (GO): Biological Process
The "Elevator Pitch" That Changed Genomics
Infectious Disease
What is DAVID? A Brief History
- Gene Ontology (GO): Biological Process, Cellular Component, Molecular Function.
- Pathway Databases: KEGG, BioCarta, Reactome, PANTHER.
- Protein Domains: InterPro, SMART, Pfam, PROSITE.
- Disease Associations: OMIM, GAD (Genetic Association Database).
- Tissue Expression: UniGene, ESTs.
- Literature: PubMed Central.
